Fig. 6
From: HK3 stimulates immune cell infiltration to promote glioma deterioration
Overexpression of Hk3 in GL261 cells promotes orthotopic tumor growth in vivo (A) Analysis of HK3 gene conservation between different species according to the UCSC database. (B) C57BL/6 N mice were orthotopically xenografted with GL261-Luc cells. (C) Bioluminescence images of C57BL/6 N mice. (D) Quantification of the signal intensities revealed by bioluminescence imaging of C57BL/6 N mice. (E) Kaplan‒Meier survival curve of C57BL/6 N mice is shown N = 10. (F) IHC staining for Ly6g, Cd206 and Cd4 in brain sections from mice tumors derived from GL261-Luc cells. Scale bar = 50 μm. The data are presented as the mean ± S.D. Significant results are presented as ns: nonsignificant, **p < 0.01, or ***p < 0.001