Fig. 7

RUNX1 play a prominent role in OV prognosis and immune landscape. A The Radar chart represented the RUNX1 gene expression in pan-cancer. B The expression distribution of RUNX1 in TCGA-OV samples and GTEx normal controls were graphed. The result proved that RUNX1 was highly expressed OV tissues. C The Kaplan–Meier (K–M) survival curves of RUNX1 in the TCGA-OV cohort, which indicated that OV patients with higher RUNX1 suffered poor survival. D The Violin diagrams showed the expression of the 22 immune cells infiltration through the CIBERSORT analysis, which indicated that memory B cells and CD4 + memory T cells were significantly upregulated in patients with high RUNX1 expression, while plasma B cells were upregulated in low-RUNX1 patients. E The UMAP diagram showed high-quality cells from a 10 × Genomics dataset [45]. Ten typical cell types were defined by specific markers. F The pseudo time trajectory analysis of 10 cell types from OV tissues. G The pseudo time trajectory analysis of cells in OV tissues with RUNX1 expression