Characteristic | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age | Â | |||
  < 55 years | Reference | − | Reference | − |
  ≥ 55 years | 1.052(0.595–1.862) | 0.861 | 1.014(0.556–1.842) | 0.97 |
FIGO stage | Â | Â | Â | Â |
 I–II | Reference | − | Reference | − |
 III–IV | 4.238(1.897–9.471) | 0.001 | 2.624(1.050–6.557) | 0.039 |
Pathology grade | Â | |||
 I–II | Reference | − | Reference | − |
 III | 0.727(0.413–1.282) | 0.271 | 0.673(0.348–1.302) | 0.239 |
Histology type | Â | 0.850 | Â | 0.934 |
 Serous | Reference | − | Reference | − |
 Mucous | 0.591(0.181–1.932) | 0.384 | 1.498(0.311–7.220) | 0.614 |
 Endometrioid | 0.875(0.341–2.245) | 0.781 | 1.305(0.475–3.585) | 0.606 |
 Other types | 0.977(0.450–2.122) | 0.953 | 1.021(0.409–2.546) | 0.965 |
Tumor diameter | Â | |||
  < 10 cm | Reference | − | Reference | − |
  ≥ 10 cm | 1.253(0.710–2.211) | 0.437 | 1.364(0.749–2.482) | 0.310 |
Serum CA125 | Â | |||
  < 35 U/ml | Reference | − | Reference | − |
  ≥ 35 U/ml | 2.680(0.960–7.486) | 0.061 | 2.093(0.511–8.572) | 0.305 |
ZBTB16 expression | Â | |||
 Low (IRS score < 8) | Reference | − | Reference | − |
 High (IRS score ≥ 8) | 5.815(3.009–11.236) | 0.001 | 5.012(2.513–9.994) | 0.001 |