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Table 4 Univariate and multivariate analysis of OV prognostic factors

From: Clinical significance and immune infiltration analyses of a novel coagulation-related signature in ovarian cancer

Characteristic

Univariate analysis

Multivariate analysis

HR (95% CI)

P-value

HR (95% CI)

P-value

Age

 

  < 55 years

Reference

−

Reference

−

  ≥ 55 years

1.052(0.595–1.862)

0.861

1.014(0.556–1.842)

0.97

FIGO stage

    

 I–II

Reference

−

Reference

−

 III–IV

4.238(1.897–9.471)

0.001

2.624(1.050–6.557)

0.039

Pathology grade

 

 I–II

Reference

−

Reference

−

 III

0.727(0.413–1.282)

0.271

0.673(0.348–1.302)

0.239

Histology type

 

0.850

 

0.934

 Serous

Reference

−

Reference

−

 Mucous

0.591(0.181–1.932)

0.384

1.498(0.311–7.220)

0.614

 Endometrioid

0.875(0.341–2.245)

0.781

1.305(0.475–3.585)

0.606

 Other types

0.977(0.450–2.122)

0.953

1.021(0.409–2.546)

0.965

Tumor diameter

 

  < 10 cm

Reference

−

Reference

−

  ≥ 10 cm

1.253(0.710–2.211)

0.437

1.364(0.749–2.482)

0.310

Serum CA125

 

  < 35 U/ml

Reference

−

Reference

−

  ≥ 35 U/ml

2.680(0.960–7.486)

0.061

2.093(0.511–8.572)

0.305

ZBTB16 expression

 

 Low (IRS score < 8)

Reference

−

Reference

−

 High (IRS score ≥ 8)

5.815(3.009–11.236)

0.001

5.012(2.513–9.994)

0.001

  1. FIGO stage Federation of International of Gynecologists and Obstetricians stage