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Fig. 2 | Cancer Cell International

Fig. 2

From: Icariin-Curcumol promotes docetaxel sensitivity in prostate cancer through modulation of the PI3K-Akt signaling pathway and the Warburg effect

Fig. 2

ECe and DTX inhibit PCa development by impeding PI3K-Akt signaling. (A) Determination of cell viability by CCK8 assay. (B) Documentation of xenograft tumor size during modeling. (C) After the nude mice were sacrificed, the weight of the xenograft tumors was recorded. (D) Representative HE staining images of tumor tissues. (E) Representative IHC staining images of Ki67 in tumor tissues. (F) Statistical analysis of Ki67 expression. (G) The relative levels of AR, PSA, PI3K, Akt1, mTOR, and HIF-1α were determined. *P < 0.05 compared with the DMSO group; #P < 0.05 compared with the Model group

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Cancer Cell International

ISSN: 1475-2867

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