Fig. 7
From: PTBP1 plays an important role in the development of gastric cancer
(A) Brief schematic of PTBP1 Cas9-KO mouse model construction. (B) After 21 days, the mice were sacrificed, photographed, and the tumors were weighed and recorded. (C, D) Weight and volume statistics of subcutaneous xenografts. (E) Observed the fluorescence intensity of subcutaneous xenografts using animal living imaging. The fluorescence intensity scale of the WT group ranged from 5.8 × 107 to 9 × 107, while that of the PTBP1 Cas9-KO group ranged from 2.8 × 107 to 8.8 × 107. (F) Immunohistochemical techniques were used to detect the expression of Ki-67 and F-actin in subcutaneous graft tumors (40x magnification, scale bar: 50 μm). * p < 0.05, ** p < 0.01 and *** p < 0.001