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Fig. 11 | Cancer Cell International

Fig. 11

From: Network pharmacology and experimental verification-based strategy for exploring the mechanisms of luteolin in the treatment of osteosarcoma

Fig. 11

Luteolin inhibits proliferation and metastasis in orthotopic OS models. (A) The body weights of the two groups (n = 6 per group) intraperitoneally treated with or without luteolin. (B) IVIS imaging of OS orthotopic mouse model after different treatments (n = 6 per group). (C) The images of excised tumors in the two groups (n = 6 per group). (D) Representative luminescence images for the two groups. (E) Representative H&E staining images of tumor, lung, and liver. Scale bar = 100 μm. All data are expressed as mean ± SD, ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001 compared to the control group, respectively

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