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Fig. 4 | Cancer Cell International

Fig. 4

From: DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress

Fig. 4

DSCC1 siRNA suppresses the metastatic potential of LUAD cells. (A) The data was collected from LinkedOmics. (B) The data was obtained from UALCAN. (C) The result was collected from TNMplot (https://tnmplot.com/analysis/). Gene expression comparison: compare tumor, normal and metastasis; Gene chip data; Gene: DSCC1; Tissue: Lung. (D) LUAD cells were transfected with DSCC1 siRNA and control siRNA for 48 h, and the migrative and invasive abilities of LUAD cells were determined by Transwell assay. (E-F) LUAD cells were transfected with DSCC1 siRNA and control siRNA for 24 h, and the migration was determined by wound healing assay. (G) LUAD cells were transfected with DSCC1 siRNA and control siRNA for 48 h, and the expression of indicated proteins were detected by western blot. (H) The data was collected from LinkedOmics.

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