Fig. 8

DSCC1 negatively correlated with tumor-infiltrating immune cells. (A-C) The data were collected from Sangerbox 3.0. Immune infiltration analysis, Immunocyte analysis (TIMER), and Immune checkpoint genes; Gene: DSCC1; Cancer: LUAD and LUSC. (D) The results were collected from TIMER (http://cistrome.org/TIMER/). (E) The data were collected from Sangerbox 3.0. (F) LUAD cells were transfected with DSCC1 siRNA and control siRNA for 48 h, and the expression of indicated proteins were determined. (G) LUAD cells were transfected with DSCC1 overexpressing plasmid and empty vector for 48 h, and the expression of indicated proteins were detected. (H) LUAD cells overexpressing DSCC1 were incubated with HSP90AB1 siRNA and control siRNA for 48 h, and the expression of indicated proteins were determined