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Fig. 1. | Cancer Cell International

Fig. 1.

From: The pyrazole derivative of usnic acid inhibits the proliferation of pancreatic cancer cells in vitro and in vivo

Fig. 1.

5, but not UA, decreases the viability of cancer cells, and noncancerous cells are less sensitive. A Chemical structures of compound 5 and UA. B-E Viability of MCF-7, PANC-1, Mia PACa-2 (cancer cells) and HDFa (noncancerous cells). Viability was measured using an MTT test after 24 or 48 h of treatment with 5 or UA at the indicated concentrations. Statistical significance between control and 5-treated cells was determined by ANOVA followed by Dunnett’s post hoc test: a—P < 0.0001, b—P < 0.001, c—P < 0.05. Experiments were performed 3–6 times in triplicate

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