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Fig. 6 | Cancer Cell International

Fig. 6

From: The pyrazole derivative of usnic acid inhibits the proliferation of pancreatic cancer cells in vitro and in vivo

Fig. 6

Derivative 5 inhibits the growth of Mia PaCa-2 cell xenografts in nude mice. Effect of 5 (400 mg/mL) or vehicle (corn oil) treatment on the tumor volumes (A) and body weights of animals (n = 9) (B). Statistical significance between the control and 5-treated groups was determined by ANOVA followed by Sidak’s post hoc test: a—P < 0.0001, b—P < 0.001. C-E: Histology of tumor (C), liver (D) or kidney (E) sections in control and 5-treated mice. Images were taken under a 10 × or 20 × objective, and representative results are shown. Tissue sections were fixed, embedded in paraffin, sectioned, and processed for H & E staining

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Cancer Cell International

ISSN: 1475-2867

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