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Table 1 Sensitivity (IC50, µg/mL) of different cancer and noncancerous cell lines to usnic acid derivative 5 after 24 or 48 h of drug treatment

From: The pyrazole derivative of usnic acid inhibits the proliferation of pancreatic cancer cells in vitro and in vivo

Origin

Cell line

IC50 (24 h)

IC50 (48 h)

breast

MCF-7

1.10

0.82

cervix

HeLa

0.66

0.29

lung

A549

0.71

0.46

liver

HepG2

0.80

0.36

colon

HCT15

2.09

1.38

pancreas

PANC-1

2.71

1.35

pancreas

Mia PaCa-2

1.96

0.90

skin fibroblasts

HDFa

4.78

1.68

  1. Each value is the mean of at least three experiments
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Cancer Cell International

ISSN: 1475-2867

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