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Fig. 8 | Cancer Cell International

Fig. 8

From: Pan-cancer analysis of NFE2L2 mutations identifies a subset of lung cancers with distinct genomic and improved immunotherapy outcomes

Fig. 8

Landscape of the microenvironment phenotypes in NSCLC. (A) Heatmap representation of TME subtype Fges from TCGA NSCLC cohort using unsupervised hierarchical clustering. Distribution of Nrf2-activating MU and Nrf2-inactivating MU according to four TME subtypes (B) and five immune subtypes (C) in TCGA NSCLC cohort. (D) Immune deconvolution using xCell enriched in Nrf2-activating MU and Nrf2-inactivating MU patients with NSCLC. (E) Violin plots of TCR Richness among Nrf2-activating mutations, Nrf2-inactivating mutations, unknown NFE2L2 mutations and WT groups

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Cancer Cell International

ISSN: 1475-2867

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