Table 3 ICD-inducing natural agents tested in different clinical trails
From: Stimulators of immunogenic cell death for cancer therapy: focusing on natural compounds
Intervention | Study Title | Conditions | Location | NCT number |
|---|---|---|---|---|
Capsaicin | Chest Pain Perception and Capsaicin Sensitivity | Chest Pain | Cooperstown, New York, United States | NCT02346903 |
Study to Evaluate the Interest of Qutenza in Patients with Head and Neck Cancer in Remission and With Sequelae Neuropathic Pain | Head and Neck Cancer | France | NCT04704453 | |
Curcumin | Effects of Curcumin on Markers of Cardiovascular Risk in Patients With CAD | Coronary Artery Disease | Universidade Federal Fluminense, Rio de Janeiro, RJ, Brazil | NCT04458116 |
Effect of Curcumin in Treatment of Squamous Cervical Intraepithelial Neoplasias (CINs) | Cervical Intraepithelial Neoplasia | Dallas, Texas, United States | NCT02554344 | |
Shikonin | The Role of Pyruvate Kinase M2 in Growth, Invasion and Drug Resistance in Human Urothelial Carcinoma | Bladder Urothelial Carcinoma | Department of Urology, National Taiwan University Hospital Taipei, Taiwan | NCT01968928 |
Silibinin | Intravenous Silibinin in Combination with Peg-interferon and Ribavirin in Non-responders | Hepatitis C | Wien, Austria | NCT00684268 |
Silibinin in NSCLC and breast cancer Patients with Single Brain metastasis | Brain Metastases, NSCLC Breast Cancer | Italy | NCT05689619 | |
Effect of Milk Thistle Derivative Silibinin(A) as a potential Anti-obesity Agent | Overweight and Obesity, Hypercholesterolemia Hypertriglyceridemia | Universidad Católica San Antonio de Murcia, Spain | NCT05069298 | |
Ginsenoside | Ginsenoside Improve Metabolic Syndrome | Metabolic Syndrome | Seoul, Kyeonggi-do, Korea, | NCT02034136 |
The Efficacy and Safety of Ginsenoside Rg3 Capsule in Prevention of Postoperative Recurrence of Hepatocellular Carcinoma | Stage I and II Hepatocellular Carcinoma | Shanghai, China | NCT01717066 | |
Resveratrol | Anti-inflammatory and Antioxidant Effects of Resveratrol on Healthy Adults | Chronic Subclinic Inflammation, Redox Status | Turin, Italy | NCT01492114 |
Resveratrol in Preventing Cancer in Healthy Participants | Unspecified Adult Solid Tumor | Michigan, United Kingdom | NCT00098969 | |
Effects of Resveratrol on Inflammation in Type 2 Diabetic Patients | Inflammation, Insulin Resistance, Type 2 Diabetes Mellitus | University of Turin, Italy | NCT02244879 | |
Lentinan | The Tolerance and Efficacy of Combined Use of Didanosine (2’,3’-Dideoxyinosine; ddI) and Lentinan in HIV-Positive Patients | HIV Infections | AJI Pharma USA | NCT00002099 |
Celastrol | Effect of Different Ingestion Doses of Celastrol on Human Sperm Motility | Safety Issues | Baton Rouge, Louisiana, United States | NCT05413226 |
Withania Somnifera | Adjunctive Withania Somnifera (Ashwagandha) for Persistent Symptoms in People with Schizophrenia | Schizophrenia | Los Angeles, California, United States | NCT03437668 |
Norcanthari-din | Phase I Clinical Study for Evaluation of Pharmacokinetic, Safety, Tolerance of Norcantharidin Lipid Microsphere for Injection in Patients with Solid Tumor | Solid Tumor | Shenyang, Liaoning, China | NCT04673396 |
Digoxin | Digoxin In Treatment of Alcohol Associated Hepatitis | Acute Alcoholic Hepatitis, Alcohol-Induced Disorders | New Haven, Connecticut, United States | NCT05014087 |
Colchicine | Effect of Combined Use of Ivermectin and Colchicine in COVID-19 Patients | COVID-19 | Cairo, Egypt | NCT05246072 |