Table 1 Clinical characteristics of HNSCC in this study
From: Prognosis of Midkine and AT1R expression in resectable head and neck squamous cell carcinoma
Patient Numbers | Percentage (%) | |
|---|---|---|
Gender | ||
Male | 142 | 94.7 |
Female | 8 | 5.3 |
Age (Median: 51 ± 9.9 years old) | ||
≦51 | 76 | 50.7 |
 > 51 | 74 | 49.3 |
Performance status (ECOG) | ||
0 | 55 | 36.7 |
1 | 68 | 45.3 |
2 | 27 | 18.0 |
Tumor site | ||
Oral | 98 | 65.3 |
Oropharynx | 24 | 16.0 |
Hypopharynx/larynx | 28 | 18.7 |
Tumor stage | ||
T1 | 10 | 6.7 |
T2 | 48 | 32.0 |
T3 | 30 | 20.0 |
T4 | 62 | 41.3 |
Lymph nodes | ||
N0 | 63 | 42.0 |
N1 | 26 | 17.3 |
N2 | 56 | 37.3 |
N3 | 5 | 3.3 |
AJCCTMN stage | ||
I | 8 | 5.3 |
II | 25 | 16.7 |
III | 26 | 17.3 |
IV | 91 | 60.7 |
P16 | ||
Positive | 19 | 12.7 |
Negative | 131 | 87.3 |
Extra-nodal extension | ||
Positive | 46 | 30.7 |
Negative | 104 | 69.3 |
Viral hepatitis | ||
No | 100 | 66.6 |
Yes | 50 | 33.3 |
Diabetes mellitus | ||
No | 94 | 62.7 |
Yes | 56 | 37.3 |
Hypertension | ||
No | 69 | 46.0 |
Yes | 81 | 54.0 |
Lyphovascular invasion | ||
No | 96 | 64.0 |
Yes | 54 | 36.0 |
Perineural invasion | ||
No | 81 | 54.0 |
Yes | 69 | 46.0 |
Adjuvant treatment | ||
No | 38 | 25.3 |
RT | 37 | 24.7 |
CCRT | 75 | 50.0 |
Smoking | ||
No | 30 | 20.0 |
Yes | 120 | 80.0 |
Alcohol | ||
No | 44 | 29.3 |
Yes | 106 | 70.7 |
Betel nuts | ||
No | 51 | 34.0 |
Yes | 99 | 66.0 |
Midkine | ||
Weak | 88 | 58.7 |
Strong | 62 | 41.3 |
AT1R | ||
Weak | 92 | 61.3 |
Strong | 58 | 38.7 |