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Fig. 6 | Cancer Cell International

Fig. 6

From: Integrative evaluation and experimental validation of the immune-modulating potential of dysregulated extracellular matrix genes in high-grade serous ovarian cancer prognosis

Fig. 6

Immune Landscape of different ECMscore groups. (A) Correlation analysis demonstrating the relationship between ECMscore and immune score, stromal score, ESTIMATE score, and tumor purity across six cohorts. (B) Heatmap illustrating normalized scores of immune cell populations in low- and high-ECMscore groups. Correlation plots (left) depict the associations between ECMscore and immune cell infiltrates. Yellow indicates positive or negative correlations, while grey represents no correlation. (C) Comparison of CD8 + T cells, M1 macrophages, fibroblasts, CYT, GEP, and IFN-γ levels between low- and high-ECMscore groups. (D) Bubble chart (upper) and Heatmap (lower) showcasing the correlation between immune modulators and ECMscore, along with their distributions in the low- and high-ECMscore groups

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Cancer Cell International

ISSN: 1475-2867

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