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Fig. 3 | Cancer Cell International

Fig. 3

From: Interplay between lncRNA RP11-367G18.1 variant 2 and YY1 plays a vital role in hypoxia-mediated gene expression and tumorigenesis

Fig. 3

RP11-367G18.1 variant 2-YY1 complex activates H4K16Ac. (A) Hypoxia enhanced H4K16Ac activation. (B) Immunofluorescence staining revealed that RP11-367G18.1 variant 2 was colocalized with YY1 and H4K16Ac in FADU cells under hypoxia. (C) Overexpression of RP11-367G18.1 variant 2 and YY1 enhanced H4K16Ac activation. For hypoxic conditions, cells were cultured in 1% O2, 5% CO2, and 94% N2 for 18 h

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