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Fig. 1 | Cancer Cell International

Fig. 1

From: Hsa_circ_0022383 promote non-small cell lung cancer tumorigenesis through regulating the miR-495-3p/KPNA2 axis

Fig. 1

Hsa_circ_0022383 expression in NSCLC tissues is dramatically upregulated. A. Volcano plot of differentially expressed circRNAs in 5 pairs of primary NSCLC tissues and adjacent nontumor tissues in GEO database. B. Clustered heatmap presenting differentially expressed circRNAs in 5 pairs of primary NSCLC tissues as well as adjacent nontumor tissues in GEO database. C. Schematic illustration of circ_0022383 formation from FADS2 through back splicing. D. Circ_0022383 expression in 60 pairs of primary NSCLC tumor tissues and adjacent nontumor tissues was calculated by qRT-PCR. E. Circ_0022383 expression in NSCLC tissues at different TNM stages was determined using qRT-PCR. F. Circ_0022383 expression in NSCLC tissues with or without lymph node metastasis was determined through qRT-PCR. G. Kaplan–Meier survival analysis of NSCLC patients with high or low circ_0022383 expression. All experiments were carried out in triplicate. “**” represents P < 0.01

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Cancer Cell International

ISSN: 1475-2867

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