Fig. 3

Hsa_circ_0022383 promotes NSCLC tumorigenesis. A. Circ_0022383 expression in NSCLC cell lines (H1299 and A549) transfected with si-NC or si-circ_0022383 was calculated by qRT-PCR. B. Cell proliferation in (A) was determined by the CCK-8 assay. C. Cell colony number in (A) was calculated by the colony formation assay. D. Cell migration capability in (A) was determined using the transwell assay. E. Tumor formation and growth in nude mice injected with NSCLC A549 cells transfected with si-NC or si-circ_0022383). F. Tumor volumes of nude mice injected with NSCLC A549 cells transfected with si-NC or si-circ_0022383. G. Tumor weight of nude mice injected with NSCLC A549 cells transfected with si-NC or si-circ_0022383. All experiments were carried out in triplicate. “**” represents P < 0.01