Skip to main content
Fig. 4 | Cancer Cell International

Fig. 4

From: Hsa_circ_0022383 promote non-small cell lung cancer tumorigenesis through regulating the miR-495-3p/KPNA2 axis

Fig. 4

Hsa_circ_0022383 regulates KPNA2 expression by sponging miR-495-3p in NSCLC cells. A. MiR-495-3p was predicted as a potential target of circ_0022383. B. Relationship between circ_0022383 and miR-495-3p was examined by the luciferase reporter assay. C. Relationship between circ_0022383 and miR-495-3p were investigated through the RNA pull-down assay. D. MiR-495-3p expression in NSCLC cell lines (H1299 and A549) transfected with si-NC or si-circ_0022383 was calculated by qRT-PCR. E. The complementary sequences of miR-495-3p and KPNA2 predicted by the StarBase database. F. Relationship between miR-495-3p and KPNA2 was calculated by the Luciferase reporter assay. G. Relationship among circ_0022383, miR-495-3p and KPNA2 was calculated by the RNA immunoprecipitation (RIP) assay. All experiments were carried out in triplicate. “**” represents P < 0.01

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us