Fig. 1

RAD51 expression is higher in oral cancer tissues and associated with poor patient prognosis. (A) Immunohistochemical stain of RAD51 (100x). Representative photo for RAD51 expression in oral non-cancerous tissues. (B) Representative photo for low RAD51 expression in oral cancer tissues. (C) Representative photo for high RAD51 expression in oral cancer tissues. (D) Quantitative result for RAD51 expression in oral non-cancerous and cancer tissues. (E) Progression free survival (PFS) in OSCC patients stratified by RAD51 expression and high RAD51 expression had a trend of shorter PFS. (F) PFS in oral squamous cell carcinoma (OSCC) patients receiving adjuvant chemotherapy stratified by RAD51 expression and high RAD51 expression had a significant shorter PFS. (G) PFS in OSCC patients receiving adjuvant radiotherapy stratified by RAD51 expression and high RAD51 expression had a significant shorter PFS. (H) Overall survival (OS) in OSCC patients stratified by RAD51 expression and high RAD51 expression had a worse OS. (I) OS in OSCC patients receiving adjuvant chemotherapy stratified by RAD51 expression and high RAD51 expression had a significant worse OS. (J) OS in OSCC patients receiving adjuvant radiotherapy stratified by RAD51 expression and high RAD51 expression had a borderline worse OS.

NS, not significant, PCI, positive stained-cell index