RAD51 is a poor prognostic marker and a potential therapeutic target for oral squamous cell carcinoma

Table 2 RAD51 protein was a poor prognostic factor for PFS in OSCC patients receiving adjuvant radiotherapy

(A)	Univariate analysis of PFS		(B)	Univariate analysis of OS
Variables	HR (95%CI)	P-value	Variables	HR (95%CI)	P-value
Sex			Sex
Male	1.00		Male	1.00
Female	0.73 (0.22–2.46)	0.610	Female	1.19 (0.27–5.27)	0.823
Age	1.02 (0.99–1.05)	0.303	Age	1.03 (0.98–1.08)	0.262
Alcohol consumption	0.74 (0.35–1.55)	0.423	Alcohol consumption	2.27 (0.64–8.07)	0.204
Betel nut chewing	1.47 (0.59–3.61)	0.406	Betel nut chewing	1.60 (0.36–7.18)	0.538
Cigarette smoking	0.95 (0.46–1.96)	0.888	Cigarette smoking	0.82 (0.29–2.33)	0.707
Stage		0.718	Stage		0.492
I, II	1.00		I, II	1.00
III, IV	0.88 (0.43–1.78)		III, IV	1.39 (0.54–3.58)
RAD51 expression		0.008*	RAD51 expression		0.069
Low expression	1.00		Low expression	1.00
High expression	3.00 (1.33–6.78)		High expression	2.67 (0.93–7.68)

(A). Univariate Cox regression analysis of progression free survival in OSCC patients with adjuvant radiotherapy. (B). Univariate Cox regression analysis of overall survival in OSCC patients with adjuvant radiotherapy
*PFS, progression-free survival; OS, overall survival; OSCC, oral squamous cell carcinoma; HR, hazard ratio; CI, confidence interval

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