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Fig. 4 | Cancer Cell International

Fig. 4

From: Whole exome sequencing identifies novel variants of PIK3CA and validation of hotspot mutation by droplet digital PCR in breast cancer among Indian population

Fig. 4

MD simulation profile of WT and MTs. (A) Root mean square deviation (RMSD measured in nanometer (nm) at function of time in nanosecond (ns), (B) Radius of gyration (Rg) measured in nm at function of time in ns, and (C) Root mean square fluctuation (RMSF) measured in nm at function of amino acid residues. WT, H1047L and H1047R MTs were labelled in black, red and blue lines, respectively. Highly fluctuated regions were highlighted in shaded rectangular boxes and indicated in regions I, II and III in RMSF graph

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