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Fig. 5 | Cancer Cell International

Fig. 5

From: Whole exome sequencing identifies novel variants of PIK3CA and validation of hotspot mutation by droplet digital PCR in breast cancer among Indian population

Fig. 5

Structural properties analyses of WT and MTs. (A) Total number of protein-protein (intra) hydrogen bond formation in time of 100ns MD simulation, (B) Total number of protein-water (inter) hydrogen bond formation in time of 100ns MD simulation, (C) Solvent accessible surface area (SASA) analyses through measurement of hydrophobic and hydrophilic SASA, and (D) Secondary structures formation throughout the simulation period. WT, H1047L and H1047R MTs were labelled in black, red and blue lines, respectively

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Cancer Cell International

ISSN: 1475-2867

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