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Fig. 2 | Cancer Cell International

Fig. 2

From: EGCG inhibits the inflammation and senescence inducing properties of MDA-MB-231 triple-negative breast cancer (TNBC) cells-derived extracellular vesicles in human adipose-derived mesenchymal stem cells

Fig. 2

Modulation of the EVs cargo by EGCG. The extracellular vesicles (EVs) were isolated from serum-starved MDA-MB-231 cells treated or not with 30 μM EGCG for 48 h. A Volcano plot for the expression profile of differentially expressed genes (DEG) with an adjusted p-value < 0.05 was selected as the threshold. B KEGG pathways enrichment analysis resulted from the comparison of DEG (EGCG-EVs vs EVs) with absolute fold change (FC) > 2, and adjusted p-value < 0.05. C Network graph showing the enriched pathways and their respective genes. Enriched terms are coloured in beige, while upregulated and downregulated genes are coloured in red and green, respectively

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Cancer Cell International

ISSN: 1475-2867

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