Table 2 Genes modulated in hypoxia vs normoxia with a p-adjusted value < 0.05 and a log2 FC > l2l
Gene Ensemble ID | log2 FC | p-adjusted value | GenCards annotations |
|---|---|---|---|
PM20D2 ENSG00000146281,6 | 4.27 | 0.032 | Peptidase M20 Domain Containing 2. Hydrolase activity. Function in metabolite repair mechanism |
FAM162A ENSG00000114023,15 | 3.52 | 0.001 | Family With Sequence Similarity 162 Member A. Hypoxia-induced cell death, the release of cytochrome C, caspase activation (CASP9) and inducing mitochondrial permeability transition |
ISCA1 ENSG00000135070,15 | 2.60 | 0.049 | Iron-Sulfur Cluster Assembly 1. Mitochondrial protein. Function in electron-transfer reactions |
ADM ENSG00000148926,10 | 2.23 | 0.001 | Adrenomedullin. Functions in vasodilation, hormone secretion regulation, angiogenesis promotion, and antimicrobial activity |
SLC2A3 ENSG00000059804,16 | 2.09 | 0.001 | GLUT3. Glucose and other monosaccharides transporter |
NIP7 ENSG00000132603,15 | − 2.20 | 0.049 | Nucleolar Pre-rRNA Processing Protein NIP7. RNA binding |
MRPS7 ENSG00000125445,11 | − 2.41 | 0.036 | Mitochondrial Ribosomal Protein S7. RNA binding and structural constituent of ribosome |
MT-TP ENSG00000210196,2 | − 2.69 | 0.032 | Mitochondrially Encoded TRNA-Pro (CCN). Associated with the tRNA class |
ZNF585A ENSG00000196967,11 | − 3.97 | 0.048 | Zinc Finger Protein 585A. Function as a transcription factor |