Fig. 5
From: Urinary biomarkers for hepatocellular carcinoma: current knowledge for clinicians
Representative urinary protein biomarkers for HCC. (A) Prognostic value of urinary protein TGF-β1 in HCC patients illustrated by Kaplan–Meier plots. Reprinted from Tsai et al., 1997. (B) Prognostic value of urinary protein MMP-2 in HCC patients as illustrated by Kaplan-Meier plots. Reprinted from Suh et al., 2014. (C). Prognostic value of urinary multiprotein models in HCC patients. (left) Co-expression of S100A9 and GRN mRNA in tumor tissues. (middle) Associated elevations in urinary S100A9 and GRN proteins. (right) Prognostic value of both S100A9 and GRN amplification/gain in HCC patients. Reprinted from Huang et al., 2015