Unveiling the role of GAS41 in cancer progression

Table 1 Summary of recognizable histone modifications of GAS41

Acylation	Histone lysine	Binding affinity KD(μM)	Target gene	Specificity	Association with cancer	References
Kac	H3K23acK27ac	13.6 ± 0.3	Unknow	Diacetylation	Unknow	[63]
	H3K27ac, H3K14ac	32.7, 13	H2AFV, H2AFZ	H2A.Z deposition	NSCLC	[31]
Kbz	H3K27bz	62.96 ± 11.24	Unknow	Open-end reader pocket	Unknow	[65]
Ksucc	H3K122succ	2.937 ± 0.21 (pH6.0), 48.34 ± 3.8 (pH7.0)	p21	pH dependent	pH imbalance	[67]
Kcr	H3K27cr	22.9	p21	Three-phase traffic light system	CRC	[57]

ISSN: 1475-2867