Fig. 4
From: Identification of a RAD51B enhancer variant for susceptibility and progression to glioma
a rs6573816 resides within POU2F1 DNA-binding motif. b ChIP assays in U251 cells with rs6573816 GG genotype. The presence of POU2F1-binding RAD51B enhancer hs1474 was verified by PCR. c Depletion of POU2F1 by RNAi attenuates the mRNA levels of RAD51B. Columns represent means; Bars indicate SE. *** P < 0.001. d Knockdown of POU2F1 by RNAi downregulates the protein levels of RAD51B