Skip to main content
Fig. 12 | Cancer Cell International

Fig. 12

From: Systematic analysis of integrated bioinformatics to identify upregulated THBS2 expression in colorectal cancer cells inhibiting tumour immunity through the HIF1A/Lactic Acid/GPR132 pathway

Fig. 12

THBS2 influences the infiltration levels, proliferation and cytotoxicity of T cells in the tumour microenvironment. A Establishment of tumour-bearing Balb/c mouse models using CT26 and CT26-THBS2 cells. Tumour size was measured after 30 days; B Flow cytometric analysis of CD3 + /CD8 + cell abundance in tumour tissues of different groups; C Flow cytometric analysis of CD3 + /CD4 + and Foxp3 + cell abundance in tumour tissues of different groups; D Flow cytometric analysis of F4/80 + /CD11b + , CD163 + and CD206 + cell abundance in tumour tissues of different groups; E Implantation of CT26-OVA and CT26-OVA-THBS2 cells into Balb/c mice, followed by intravenous injection of CD8 + T cells from OT-1 mice for treatment. Tumour size was measured on day 0; F: Flow cytometric analysis of CFSE in tumour tissues

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us