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Fig. 13 | Cancer Cell International

Fig. 13

From: Systematic analysis of integrated bioinformatics to identify upregulated THBS2 expression in colorectal cancer cells inhibiting tumour immunity through the HIF1A/Lactic Acid/GPR132 pathway

Fig. 13

Immunosuppressive phenotype induced by high expression of THBS2 depends on GPR132 expression. A Establishment of GPR132-KO and tumour-bearing Balb/c mouse models; B Assessment of tumour size 30 days after the injection of CT26 and CT26-THBS2 cells in mice; C Flow cytometric analysis of CD3 + /CD8 + and TIM3 + /PD1 + cell abundance in tumour tissues of different groups. D Flow cytometric analysis of F4/80 + /CD11b + , CD163 + and CD206 + cell abundance in tumour tissues of different groups; E Flow cytometric analysis of CFSE in CD8 + T cells

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Cancer Cell International

ISSN: 1475-2867

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