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Fig. 5 | Cancer Cell International

Fig. 5

From: Systematic analysis of integrated bioinformatics to identify upregulated THBS2 expression in colorectal cancer cells inhibiting tumour immunity through the HIF1A/Lactic Acid/GPR132 pathway

Fig. 5

THBS2 methylation in pan-cancer. A–E Box plots demonstrating differences in THBS2 methylation levels between normal and tumour tissues in pan-cancer; red represents tumour tissues; blue represents normal tissues; p-values represent significant differences; F Radar plot demonstrating the correlation between methylation levels and THBS2 expression at cg21652958 locus in pan-cancer; G–I KM curves demonstrating OS in the high- and low-cg21652958-methylation groups; orange represents the high-cg21652958-methylation group; green represents the low-cg21652958-methylation group; p-values represent significant differences; J Radar plot demonstrating the correlation between the methylation levels of cg21732383 and THBS2 expression in pan-cancer; K–M Radar plot demonstrating differences in OS between the high- and low-cg21732383-methylation groups based on KM curves

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