Fig. 6

Expression of THBS2 in COAD. A Stick plot demonstrating the correlation between THBS2 expression and the enrichment scores of the HALLMARK gene set; the size of the dots represents a strong correlation; the right side represents a positive correlation; the left side represents a negative correlation; the colour represents p-values; the smaller the p-value, the more significant the correlation; B Protein–protein interaction network of THBS2 constructed using the STRING database; C Stick plots demonstrating the correlation between the expression of THBS2 and that of other proteins in the network; D Heat map of differential expression of copper death- and iron death-related genes between the high- and low-THBS2-expression groups; E Bubble plots of KEGG, GO-BP (biological process), GO-MF (molecular function) and GO-CC (cellular component) enrichment analyses of marker genes in the high-THBS2-expression group; the size of the dots represents the number of enriched differentially expressed genes; the colour represents the significance of the enrichment