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Fig. 8 | Cancer Cell International

Fig. 8

From: Systematic analysis of integrated bioinformatics to identify upregulated THBS2 expression in colorectal cancer cells inhibiting tumour immunity through the HIF1A/Lactic Acid/GPR132 pathway

Fig. 8

Genomic mutations associated with THBS2 in COAD. A Waterfall plot demonstrating the SNV frequency of top 20 genes in TCGA-COAD cohort; B Heat map demonstrating the co-linearity and mutual exclusivity of top 10 mutated genes in the high-THBS2-expression group; C Heat map demonstrating the co-linearity and mutual exclusivity of top 10 mutated genes in the low-THBS2-expression group; D Forest plot demonstrating differences in the mutation frequency of top 100 genes between the high- and low-THBS2-expression groups, with p-values representing significant differences; E, F Box plots demonstrating differences in TMB and TNB between the mutant-THBS2 (MT) and wildtype-THBS2 (WT) groups; G Heat map demonstrating the co-linearity and mutual exclusivity of top 10 mutated genes in the MT group

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Cancer Cell International

ISSN: 1475-2867

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