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Fig. 1 | Cancer Cell International

Fig. 1

From: Canine diffuse large B-cell lymphoma downregulates the activity of CD8 + T-cells through tumor-derived extracellular vesicles

Fig. 1

Significant decrease in CD3 + CD8 + double-positive T cells in dogs with DLBCL. A Representative flow cytometric figures of PBMCs isolated from healthy dogs and B dogs with DLBCL. C Statistical analysis of B and T cell subtypes proportions in dogs with or without DLBCL. Bar graphs reflect mean ± SD (n = 5) analyzed by the unpaired Student t-test. FSC forward scatter, SSC side scatter, DLBCL diffuse large B-cell lymphoma, PBMCs peripheral blood mononuclear cells; ***, P < 0.001; ****, P < 0.0001; n.s., no significant difference

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