Fig. 5
From: Exosomal circRNA RHOT1 promotes breast cancer progression by targeting miR-204-5p/ PRMT5 axis
CircRHOT1 functions as a sponge of miR-204-5p. A, The potential interaction between circRHOT1 and miR-204-5p. B, The luciferase activities of WT-circRHOT1 and MUT circRHOT1 with miR-204-5p. C, Expression of miR-204-5p in normal control (n = 10) and breast cancer patients (n = 10). D, Expression of miR-204-5p in MCF-10 A and MCF-7. E, Expression of circRHOT1 after overexpression or knockdown. F, Expression of miR-204-5p after circRHOT1 overexpression or knockdown. G, Quantitative real-time PCR analysis of circRHOT1 after treatment with RNase R. H, Correlation between circ-RHOT1 and miR-204-5p. ** p < 0.01, *** p < 0.001