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Fig. 8 | Cancer Cell International

Fig. 8

From: Exosomal circRNA RHOT1 promotes breast cancer progression by targeting miR-204-5p/ PRMT5 axis

Fig. 8

Exosomal circRHOT1 promoted the proliferation, migration, and invasion of MCF-7 via PRMT5. A, The expression of PRMT5 among different treatment groups. B, Cell proliferation assessed by MTT assay. C, Colony formation assay results. D, Flow cytometry analysis of apoptosis. E, Wound healing assay results. F, Transwell assay of migration results. G, Western blot analysis of E-cadherin, N-cadherin, and vimentin expression. Compared with si-NC + pcDNA and si-circRHOT1 + pcDNA group, *P < 0.05, ** p < 0.01, *** p < 0.001

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