Fig. 5
From: HADHA promotes ovarian cancer outgrowth via up-regulating CDK1
HADHA promoted ovarian cancer tumor outgrowth by upregulating CDK1. (A, B) The weight (A) and volume (B) of tumor, derived from HO-8910 cells with lentiviruses for CDK1 knockdown and/or HADHA overexpression, were measured. (C) The photos of tumor collected from mice. (D) Western blot assay presented HADHA and CDK1 levels in tumor tissues. (E) IHC staining visualized the expression pattern of Ki67 in tumor tissues with CDK1 knockdown and/or HADHA overexpression. NC (OE + KD): Control; CDK1 + NC (KD): CDK1 overexpression; shHADHA + NC (OE): HADHA downregulation; CDK1 + shHADHA: CDK1 overexpression and HADHA downregulation