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Fig. 6 | Cancer Cell International

Fig. 6

From: Tumor-derived exosomal linc00881 induces lung fibroblast activation and promotes osteosarcoma lung migration

Fig. 6

Linc00881 activates lung fibroblasts through the NF-κB axis. A, B. Western blotting analysis of the proteins of NF-κB axis in HFL-1 cells treated with exosomes from MG63 and HOS cells. C, D. Western blotting analysis of the expression of MMP2 and N-cadherin in HFL-1 cells treated with MG63 or HOS cell-derived exosomes. E, F. Western blotting analysis of the proteins of NF-κB axis in HFL-1 cells treated with: a. control vector, b. linc00881 vector, c. control siRNA, d. MMP2 siRNA, e. control MMP2, and f. MMP2 vector. G, H. Western blotting analysis of the expression of MMP2 and N-cadherin in HFL-1 cells in different treatments as described in E. (*p < 0.05; **p < 0.01; *** p < 0.0001)

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Cancer Cell International

ISSN: 1475-2867

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