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Fig. 2 | Cancer Cell International

Fig. 2

From: Impact of ARID1A and TP53 mutations in pediatric refractory or relapsed mature B-Cell lymphoma treated with CAR-T cell therapy

Fig. 2

Gene mutations of TP53 and ARID1A in r/r MB-NHL and initial remission patients. (a) Co-mutations between genes in cases with IR Mb-NHL (left) and (b) r/r MB-NHL (right). The red lines indicate co-mutations of TP53 and ARID1A. (c) The location of amino acid changes resulting from TP53 and (d) ARID1A mutations. The upper part indicates IR MB-NHL and the lower part indicates r/r MB-NHL patients. The length of the line indicates the number of mutations. R248 W/V (c) is a hot spot mutation in TP53 in initial remission, and R273H/C (c) is a hot spot mutation in TP53 in r/r MB-NHL

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Cancer Cell International

ISSN: 1475-2867

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