Skip to main content
Fig. 11 | Cancer Cell International

Fig. 11

From: Leveraging a disulfidptosis/ferroptosis-based signature to predict the prognosis of lung adenocarcinoma

Fig. 11

Validates the role of the key gene GMPR in lung cancer cell lines in vitro. A The overexpression of GMPR significantly enhanced its expression in the A549 and PC9 cell lines (**P < 0.001). B After the overexpression of GMPR in A549 and PC9 cell lines, the activity of lung adenocarcinoma cells significantly decreased (**P < 0.01, ***P < 0.001). C Clone formation assay results showed that the ability of colony formation in A549 and PC9 cell lines was significantly reduced after GMPR overexpression (**P < 0.01). D The control group demonstrated a stronger migration ability than the experimental group in the wound healing experiment in A549 and PC9 cell lines (**P < 0.01, ***P < 0.001). E Overexpression of GMPR attenuated the invasive ability of A549 and PC9 cell lines (*P < 0.05, ***P < 0.001)

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us