Fig. 9

Mutational landscape differential analysis of risk subtypes and construction of a nomogram. A Overview of the top 20 mutated genes in high-risk and low-risk populations. The bars above show the total amount of gene mutations and the corresponding mutation types. The right column displays the mutation frequency of the top 20 mutated genes. B Nomogram for 1-, 3-, and 5-year overall survival prediction. The red line shows an example of predicting the prognosis. C Calibration plots for agreement tests between predicted and actual OS. D KM analysis was used to compare the differences in survival between high and low nomogram score groups. E ROC analysis was used to evaluate the ability and accuracy of the nomogram