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Table 1 List of 27 EV differential proteins with significant interesting from H. pylori infected GES-1 cells

From: The proteomics analysis of extracellular vesicles revealed the possible function of heat shock protein 60 in Helicobacter pylori infection

Number

Protein

Protein name

Gene

Proteins

Peptides

Unique peptides

Coverage

Mol/weight

Expression pattern

1

E9PPJ5

Midkine (Fragment)

MDK

2

5

5

39.7

14.374

Up

2

A0A0S2Z3X8

Rab GDP dissociation inhibitor (Fragment)

GDI1

6

13

7

43

50.582

Up

3

Q5TZZ9

Annexin

ANXA1

29

21

21

64.2

38.714

Up

4

A0A590UJ76

Deleted in malignant brain tumors 1 protein

DMBT1

5

3

3

6

260.63

Up

5

Q9UEY4

Anion exchange protein

SLC4A2

16

16

16

23.5

135.58

Up

6

A0A024R3X4

60 kDa chaperonin (Fragment)

HSPD1

24

19

19

46.8

61.054

Up

7

E9PN41

Tetraspanin-4 (Fragment)

TSPAN4

7

4

4

47.7

15.195

Up

8

B4DN67

Kin of IRRE-like protein 1

KIRREL1

3

7

7

16.3

72.721

Up

9

A0A024R7S3

Clathrin light chain

CLTB

3

6

6

26.1

23.181

Up

10

H3BTI0

Cysteine-rich secretory protein LCCL domain-containing 2

CRISPLD2

4

7

7

21.6

55.79

Up

11

Q6NVI1

MARCKS protein (Fragment)

MARCKS

2

8

8

83.4

14.859

Up

12

B4DEX8

S-adenosylmethionine synthase

MAT2A

5

9

7

37.6

39.71

Up

13

A0A494C017

Myeloid-associated differentiation marker (Fragment)

MYADM

7

1

1

18.9

13.153

Up

14

F6SDV2

Tubulointerstitial nephritis antigen-like

TINAGL1

1

11

3

56.4

40.867

Down

15

Q86UY0

TXNDC5 protein

TXNDC5

4

8

8

33.1

40.369

Down

16

Q6FIG4

RAB1B protein

RAB1B

2

8

0

52.7

22.198

Down

17

E9PNF7

Lysosomal Pro-X carboxypeptidase

PRCP

11

5

5

20.8

49.902

Down

18

A0A024RC33

Microtubule-associated protein RP/EB family member 2

MAPRE2

3

9

2

36.7

37.031

Down

19

Q1HBJ4

Mitogen-activated protein kinase

MAPK1

9

8

8

27.2

41.389

Down

20

A0A1S5UZ25

Mediator of ErbB2-driven cell motility 1

Memo1

2

5

1

29.2

30.051

Down

21

Q53Y83

Alpha-galactosidase

GLA

12

8

8

24.9

48.766

Down

22

A8K0F7

Vitamin-K-epoxide reductase (warfarin-sensitive)

 

2

2

2

11.9

19.775

Down

23

F8W6G1

Nuclear receptor-binding protein

NRBP1

3

5

5

13.8

60.829

Down

24

Q6PKI6

YBX1 protein (Fragment)

YBX1

6

11

3

62

29.374

Down

25

F6SDV2

Tubulointerstitial nephritis antigen-like

TINAGL1

1

11

3

56.4

40.867

Down

26

Q86UY0

TXNDC5 protein

TXNDC5

4

8

8

33.1

40.369

Down

27

Q6FIG4

RAB1B protein

RAB1B

2

8

0

52.7

22.198

Down