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Fig. 3 | Cancer Cell International

Fig. 3

From: Prognostic potential of whole exome sequencing in the clinical management of metachronous colorectal cancer liver metastases

Fig. 3

Relative contribution of top mutational signatures in mCLM. Top – relative exposures of top 9 SBS signatures in each sample. Bottom: top_SBSs – cosine similarity of the mutational catalog reconstructed from 9 most dominant signatures (above) to the original data. full_COSMIC_v3.3 – cosine similarity when fitting the full set of 79 COSMIC reference signatures (version 3.3). Few samples showed a substantial decrease in fitting accuracy by reduction of the number of signatures from 79 to 9

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Cancer Cell International

ISSN: 1475-2867

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