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Fig. 5 | Cancer Cell International

Fig. 5

From: Prognostic potential of whole exome sequencing in the clinical management of metachronous colorectal cancer liver metastases

Fig. 5

Kaplan-Meier plots of patient survival stratified by the carriage of variants in HRR, oncodriver pathways, and individual genes. (A) RFS analysis of somatic variants with HIGH functional effect in the HRR gene panel [30]. (B) RFS analysis of (A) complemented with rare pathogenic HRR variants. RFS analyses of somatic variants with HIGH or MODERATE functional effect in the MYC (C), Notch (D), and Hedgehog (E) pathways. OS analysis of somatic variants with HIGH or MODERATE functional effect in the JAK-STAT pathway (F), VIPR2(G), and MUC16 (H). Red line represents patients carrying the variant, and the blue line those without. HR = hazard risk

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Cancer Cell International

ISSN: 1475-2867

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