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Fig. 1 | Cancer Cell International

Fig. 1

From: Holothurian triterpene glycoside cucumarioside A2-2 induces macrophages activation and polarization in cancer immunotherapy

Fig. 1

Strategy of cellular anticancer immunotherapy. Mouse macrophages were activated with sea cucumber triterpene glycoside cucumarioside A2-2 (CA2-2) and polarized in M1 tumoricidal phenotype ex vivo. Then, macrophages were loaded with synthesized nanoparticles conjugated with near-infrared fluorescent probe CyTE777 (NIR-NPs). After that, activated and polarized fluorescent M1 macrophages were injected into tumor bearing mice for macrophage visualization and localization and for anticancer cellular immunotherapy

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Cancer Cell International

ISSN: 1475-2867

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