Skip to main content
Fig. 2 | Cancer Cell International

Fig. 2

From: The interconnected roles of TRIM21/Ro52 in systemic lupus erythematosus, primary Sjögren’s syndrome, cancers, and cancer metabolism

Fig. 2

A summarized mechanism(s) that SLE or pSS may lead to an increased risk of lymphoma and a decreased risk of breast cancer. Down-regulation of TRIM21/Ro52 expression is associated with poor overall survival in both lymphoma and breast cancer. IKKβ: kappa‐B kinase subunit beta; SALL-4: spalt like transcription factor 4; SET7/9: SET domain containing 7, histone lysine methyltransferase; TβRII: growth factor beta receptor 2

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us