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Fig. 1 | Cancer Cell International

Fig. 1

From: DHRS4-AS1 regulate gastric cancer apoptosis and cell proliferation by destabilizing DHX9 and inhibited the association between DHX9 and ILF3

Fig. 1

LncRNA DHRS4-AS1 is downregulated in gastric cancer. (A) Hierarchical clustering analysis of differentially expressed lncRNAs (fold change > 2; P < 0.05) in gastric cancer and normal tissues in gastric cancer and normal tissues. (B) overlap of misregulated lncRNAs in GEO datasets and our sequencing data. (C) Relative DHRS4-AS1 expression was analyzed by qRT-PCR in 68 GC tissue samples. (D) Relative DHRS4-AS1 levels in GC cell lines and normal human normal gastric mucosal epithelial cells. (E) LncRNA DHRS4-AS1 expression in GC tissue was analyzed by in situ hybridization. (F) The association between DHRS4-AS1 and OS was analyzed in our institution cohort. (G and H) Kaplan–Meier Survival Plots (K-M plots) analysis of the OS and PFS of GC patients based on DHRS4-AS1 expression. *p < 0.05, **p < 0.01, and ***p < 0.001

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Cancer Cell International

ISSN: 1475-2867

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