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Table 2 Univariate and multivariate Cox Regression analysis of prognostic factors of the 125 OV patients

From: Anoikis-related signature predicts prognosis and characterizes immune landscape of ovarian cancer

Characteristic

Univariate Analysis

Multivariate Analysis

HR (95% CI)

P-value

HR (95% CI)

P-value

Age

    

 < 55 years

Reference

–

Reference

–

 ≥ 55 years

1.052(0.595–1.862)

0.861

1.189(0.652–2.167)

0.573

FIGO stage

    

 I–II

Reference

–

Reference

–

 III–IV

4.238(1.897–9.471)

0.001

3.873(1.465–10.239)

0.006

Pathology stage

    

 I–II

Reference

–

Reference

–

 III

0.727(0.413–1.282)

0.271

0.731(0.373–1.431)

0.360

Histology type

 

0.850

 

0.589

 Serous

Reference

–

Reference

–

 Mucous

0.591(0.181–1.932)

0.384

1.902(0.390–9.286)

0.427

 Endometrioid

0.875(0.341–2.245)

0.780

0.910(0.330–2.510)

0.855

 Other types

0.977(0.450–2.122)

0.953

1.676(0.679–4.138)

0.263

Tumor diameter

    

 < 10 cm

Reference

–

Reference

–

 ≥ 10 cm

1.253(0.710–2.211)

0.437

1.483(0.796–2.764)

0.215

Serum CA125

    

 < 35 U/ml

Reference

–

Reference

–

 ≥ 35 U/ml

2.680(0.960–7.486)

0.060

1.202(0.304–4.754)

0.793

DAPK1 expression

    

 Low (IRS score < 6)

Reference

–

Reference

–

 High (IRS score ≥ 6)

5.994(3.290–10.921)

0.001

5.196(2.789–9.681)

0.001

  1. FIGO stage Federation of International of Gynecologists and Obstetricians stage, HR hazard ratio, 95% CI 95% confidence interval