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Table 2 SNORNAs expression levels of HCC in relation to clinical and pathological

From: TEP SNORD12B, SNORA63, and SNORD14E as novel biomarkers for hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC)

Parameters in a series of 117 HCC

Samples

SNORD12B

SNORD14E

SNORA63

 

Mean ± SD

P value

Mean ± SD

P value

Mean ± SD

P value

Male

92

11.81 ± 1.642

0.5573

3.942 ± 2.397

0.5266

6.048 ± 2.51

0.8186

Female

25

11.63 ± 1.818

 

3.706 ± 2.485

 

5.918 ± 2.502

 

Age(Year ≤ 60)

57

11.78 ± 1.468

0.6668

3.891 ± 2.5

0.8375

5.71 ± 2.396

0.1914

Age(Year>60)

60

11.77 ± 1.863

 

3.893 ± 2.336

 

6.315 ± 2.575

 

Not-smoking

72

11.8 ± 1.769

0.99

3.677 ± 2.655

0.8638

5.947 ± 2.48

0.6884

Smoking

45

11.73 ± 1.531

 

4.236 ± 1.924

 

6.138 ± 2.55

 

Not-drinking

73

11.85 ± 1.825

0.7654

3.6 ± 2.584

0.3747

5.905 ± 2.533

0.5209

Drinking

44

11.65 ± 1.403

 

4.375 ± 2.016

 

6.212 ± 2.455

 

TNM Stage

       

I

17

11.46 ± 1.721

0.2227

4.415 ± 2.164

0.1516

5.483 ± 1.854

0.5497

II

37

12.28 ± 1.874

 

4.148 ± 2.746

 

6.18 ± 2.532

 

III

45

11.63 ± 1.445

 

3.636 ± 2.254

 

6.23 ± 2.494

 

IV

18

11.4 ± 1.626

 

3.51 ± 2.293

 

5.676 ± 3.011

 

T Stage

       

T1

22

11.23 ± 1.651

0.1148

3.68 ± 3.057

0.1383

4.885 ± 2.094

0.1029

T2

9

11.1 ± 1.599

 

2.717 ± 1.029

 

5.737 ± 2.686

 

T3

34

11.56 ± 1.446

 

3.645 ± 2.115

 

5.99 ± 2.59

 

T4

25

12.2 ± 1.672

 

4.163 ± 2.595

 

6.727 ± 2.665

 

Not available

27

12.32 ± 1.829

 

4.515 ± 2.239

 

6.423 ± 2.288

 

LN metastasis

       

N1

72

11.62 ± 1.614

0.2762

3.755 ± 2.483

0.043

5.927 ± 2.462

0.271

N2

14

11.08 ± 1.39

 

3.32 ± 2.551

 

5.116 ± 2.733

 

Not available

31

12.45 ± 1.757

 

4.468 ± 2.108

 

6.645 ± 2.395

 

Distant metastasis

       

M1

74

11.62 ± 1.613

0.7592

3.706 ± 2.46

0.3919

5.952 ± 2.496

0.6624

M2

15

11.48 ± 1.608

 

3.687 ± 2.482

 

5.631 ± 2.995

 

Not available

28

12.34 ± 1.798

 

4.492 ± 2.2

 

6.41 ± 2.246

 
  1. Bold values indicate statistically significantpvalues (p < 0.05)