Table 2 Genotype analysis of rs1199520604 PRKCI G34W and rs1197750201 PRKCI F66Y
From: Possible prognostic impact of PKCι genetic variants in prostate cancer
Genotype | Patient (n = 100) | Control (n = 100) | Odds Ratio | 95% CI Odds Ratio | Relative risk | 95% CI Relative risk | P value |
|---|---|---|---|---|---|---|---|
n. (%) | n. (%) | ||||||
rs1199520604 PRKCI G34W | |||||||
GG | 36 (36%) | 56 (56%) | 0.4222 | 0.2422 to 0.7467 | 0.6483 | 0.4771 to 0.8630 | 0.0031 |
TT | 6 (6%) | 20 (20%) | 0.2609 | 0.1036 to 0.6537 | 0.4314 | 0.2039 to 0.8024 | 0.0055 |
GT | 58 (58%) | 24 (24%) | 4.373 | 2.411 to 8.041 | 1.987 | 1.510 to 2.646 | < 0.0001 |
G | 65 (65%) | 68 (68%) | 0.8739 | 0.4834 to 1.568 | 0.9356 | 0.7093 to 1.264 | 0.7646 |
T | 35 35% | 32 (32%) | 0.2534 | 0.1448 to 0.4642 | 0.5071 | 0.3709 to 0.6799 | < 0.0001 |
rs1197750201 PRKCI F66Y | |||||||
TT | 57 (57%) | 24 (24%) | 4.198 | 2.317 to 7.703 | 1.947 | 1.482 to 2.586 | < 0.0001 |
AT | 8 (8%) | 16 (16%) | 0.4565 | 0.1929 to 1.100 | 0.1264 | 0.3390 to 1.048 | 0.1264 |
AA | 35 (35%) | 60 (60%) | 0.3590 | 0.2020 to 0.6431 | 0.5951 | 0.4352 to 0.7978 | 0.0006 |
A | 39 (39%) | 68 (68%) | 0.3009 | 0.1658 to 0.5457 | 0.5557 | 0.4124 to 0.7377 | < 0.0001 |
T | 61 (61%) | 32 (32%) | 3.324 | 1.800 | 1.355 to 2.425 | < 0.0001 | |